新闻

2026

A collaborative study involving our group, “In situ particle-to-fibre transformation of hydrogels for 3D printing,” has been published in Nature.

In this work, the authors report shear-extensional in situ particle-to-fibre transformation (SHIFT), a new biofabrication strategy that transforms hydrogel particles into highly aligned microfibres during extrusion. By creating subvoxel fibrous architectures directly within printed constructs, SHIFT introduces pronounced structural anisotropy into soft hydrogels and provides a versatile approach for hierarchical tissue fabrication.

The resulting anisotropic structures promoted the formation of exceptionally long, aligned myotubes and accelerated skeletal muscle regeneration in a volumetric muscle loss model. Our team contributed to the skeletal muscle regeneration experiments and characterization. This work expands the capabilities of 3D bioprinting for constructing structurally organized and functionally regenerative tissues.

The 12th WACBE World Congress on Bioengineering, Changzhou
第十二届 WACBE 世界生物工程大会，常州
Hierarchical Tissue Manufacturing via Biofabrication and Bioassembly
基于生物制造与生物组装的组织层级化构建
Prof. Qi Gu, Invited Speaker

Wiley Editorial Office, Beijing
Wiley编辑部，北京
3D Bioprinting and Organ Fabrication
3D生物打印与器官制造
Prof. Qi Gu, Invited Speaker for the Special Feature on 3D Printing

We are excited to share that our review, “Advancing Stem Cell Bioprinting to Bridge Engineered and Natural Tissue Constructs,” has been featured on the back cover of Advanced Materials (Volume 38, Issue 42).

In this review, we summarize recent progress in stem-cell-based organ manufacturing and highlight strategies for developmentally inspired tissue fabrication. By integrating intrinsic cellular programs, including genetic networks and self-organization, with extrinsic engineering cues such as bioink dynamics, microfabrication, and mechanical regulation, we propose a conceptual framework that brings instructive bioprinting together with autonomous development.

The cover depicts stem-cell biomanufacturing as a vibrant “Life Tree.” The DNA-helix trunk, robotic bioprinter, and hydrogel-rooted living bioinks symbolize the convergence of biological programming and precision fabrication, while the organ-like canopy illustrates stem-cell self-organization, maturation, and functional tissue formation. Together, these elements envision a path toward bridging engineered tissue constructs with natural regeneration.

Stem Cell-Based Biomanufacturing: The Life Tree

The 28th Annual Meeting of the China Association for Science and Technology (CAST): Organoid Forum — AI-Driven Intelligent Manufacturing of Organoids and a New Paradigm for Drug Evaluation
第二十八届中国科协年会类器官专题论坛——AI驱动的类器官智造与药物评价新范式
3D Bioprinting and Multiscale Tissue Construction
生物3D打印与多尺度组织构建
Prof. Qi Gu, Invited Speaker and Panelist

The 6th International Conference on Biomaterials, Bio-Design and Manufacturing (BDMC 2026), The Chinese University of Hong Kong, Hong Kong
第六届国际生物材料、生物设计与制造大会（BDMC 2026），香港中文大学，中国香港
Hierarchical Fabrication of Physiological Structures
生理结构的多层级构建
Prof. Qi Gu, Session Organizer and Keynote Speaker

We are excited to share that our study, “Cryopreservative Bioink Enables Direct Bioprinting of Adherent Cells,” has been featured on the cover of Advanced Materials (Volume 38, Issue 40).

In this work, we developed CAMP (Cryopreservation for Adhesion and Maintenance Printing), a DMSO-free bioink platform that preserves adherent cells during liquid nitrogen storage and enables direct 3D bioprinting at 4–8°C after thawing. By inhibiting ice recrystallization and maintaining cell adhesion, CAMP achieves approximately 80% cell viability and integrates cryopreservation, bioprinting, and functional tissue formation into a streamlined workflow. In a rat femoral defect model, cryopreserved CAMP constructs promoted complete bone regeneration within three months.

The cover depicts snow-covered mountains and glaciers as the cryogenic environment, while bioprinted tissues emerge as wintersweet blossoms. Inspired by the resilience of wintersweet blooming through the bitter cold, the artwork illustrates how cryopreserved cells can develop into robust and functional tissues through precise bioprinting. This work advances on-demand biofabrication toward ready-to-use and clinically applicable engineered tissues.

The 28th Annual Meeting of the China Association for Science and Technology (CAST): Thematic Forum on Applications of Synthetic Biology in Medicine
第二十八届中国科协年会专题论坛——合成生物学在医学中的应用
Prof. Qi Gu, Invited Panelist

2026 Beijing Neuroscience Development Forum, Beijing
2026北京神经科学发展论坛，北京
3D Bioprinting and Neural Tissue Construction
生物3D打印与神经组织构建
Prof. Qi Gu, Invited Speaker

European Research and Technology Centre (ERTC) | Follow-Up Workshop Heilbronn
ERTC后续研讨会，德国海尔布隆
Engineering Tissue Architecture by Multilevel Biofabrication
基于多层级生物制造的组织结构工程
Prof. Qi Gu, Chinese Delegation Leader and Invited Speaker

The 1st National Annual Conference on Volume Electron Microscopy and Biomedical Applications, Beijing
第一届全国体电子显微学和生物医药应用学术年会，北京
Multiscale Physiological Structure Assembly and Fabrication
多尺度生理结构组装与制造
Prof. Qi Gu, Invited Speaker

2026 Annual Meeting of the Advanced Manufacturing Branch of the Chinese Society for Biomaterials & High-End Forum on 3D Bioprinting, Hangzhou
2026中国生物材料学会生物材料先进制造分会学术年会暨生物3D打印高端论坛，杭州
Multiscale Physiological Structure Assembly and Fabrication
多尺度生理结构组装与制造
Prof. Qi Gu, Session Keynote Speaker

Advanced Training Course on Neural Organoid Technologies, Branch of Neural Stem Cells and Tissue Engineering, Chinese Neuroscience Society, Nanjing
中国神经科学学会神经干细胞与组织工程分会神经类器官前沿技术培训班，南京
Prof. Qi Gu, Invited Speaker

The 14th Shanghai Society for Cell Biology – Cell Death (SSCB-CD) Symposia: The 2nd Symposium on Frontiers in Neural Organoids & Hengshan Forum
第十四期SSCB-CD Symposia，第二届神经类器官前沿研讨会暨衡山论坛
Strategies for Constructing Multiscale Neural Tissues
多尺度神经组织构建策略
Prof. Qi Gu, Invited Speaker

Multidisciplinary Diagnosis and Treatment Alliance, National Center for Orthopaedic Medicine
2026年国家骨科医学中心骨质疏松骨折多学科诊疗联盟专家学术交流项目
Organ Manufacturing and Functional Simulation
器官制造与功能模拟
Prof. Qi Gu, Invited Speaker

The 2nd International Organoid Conference, Jiangwan Campus, Fudan University, Shanghai
第二届国际类器官会议，上海复旦大学江湾校区
Hierarchical Physiological Structure Fabrication and Functional Simulation
多层级生理结构制造与功能模拟
Prof. Qi Gu, Session Invited Speaker

PhD Dissertation Defense
Wenhui Huang, Kai Li, and Tan Jia have successfully defended their doctoral dissertations. Congratulations on your graduation and best wishes for your next adventure, Dr. Huang, Dr. Li, and Dr. Jia!
Master’s Thesis Defense
Congratulations to our graduate students, Haolin Chen and Shuxian Chen!

The 9th National Symposium on Cell Bioinformatics, Taixing, Jiangsu
第九届全国细胞生物信息学研讨会，江苏泰兴
Hierarchical Tissue Manufacturing via Biofabrication and Bioassembly
多层级生理结构组装与制造
Prof. Qi Gu, Invited Speaker

Congratulations to Prof. Qi Gu on Being Selected as a Finalist for the 2nd Wiley Star Scientist Award
Prof. Qi Gu was selected as a finalist for the 2nd Wiley Star Scientist Award in the field of Interdisciplinary Sciences. This recognition highlights his innovative potential and research contributions in biomaterials and 3D printing, and reflects the vitality and promise of outstanding young scientists in advancing future scientific discovery.

The 10th National Youth Scientist Forum on Additive Manufacturing, Beijing
第十届全国增材制造青年科学家论坛，北京
Hierarchical Tissue Manufacturing via Biofabrication and Bioassembly
多层级生理结构组装与制造
Prof. Qi Gu, Session Keynote Speaker

We are excited to share that our latest study, “Nanoengineered extrusion-aligned tract bioprinting enables functional repair of spinal cord injuries,” has been selected as a cover article in Cell Stem Cell.
In this work, we introduce a nanoengineered bioprinting strategy that harnesses shear forces during extrusion to generate continuous, hierarchically aligned tissue tracts—spanning from nanoscale collagen fibrils to centimeter-scale constructs—without post-processing. This platform enables precise guidance of neural cells and axons, and demonstrates robust functional recovery in spinal cord injury models. The cover highlights a new paradigm in biofabrication for building anisotropic, regenerative tissues with clinically relevant dimensions.

2026 Frontiers and Interdisciplinary Conference on Synthetic Biology, Shenzhen
2026年合成生物学前沿交叉会议，深圳
Hierarchical Tissue Manufacturing via Biofabrication and Bioassembly
多层级生理结构组装与器官制造
Prof. Qi Gu, Session Keynote Speaker and Session Chair

Beijing Friendship Hospital, Capital Medical University
首都医科大学附属北京友谊医院
Hierarchical Tissue Manufacturing via Biofabrication and Bioassembly
多层级生理结构组装与器官制造
Prof. Qi Gu, Invited Speaker

Academic Forum, The Third Affiliated Hospital of Air Force Medical University
空军军医大学口腔医院学术论坛
Hierarchical Tissue Manufacturing via Biofabrication and Bioassembly
Prof. Qi Gu, Invited Speaker

Institute of Process Engineering, Chinese Academy of Sciences, Beijing
中国科学院过程工程研究所
Hierarchical Tissue Biofabrication and Bioassembly
Prof. Qi Gu, Invited Speaker

News Archive

2025

Awards:

Fellow of the Royal Society of Chemistry (FRSC)
Second Place at the 5th Tug of War, Beijing Institute for Stem Cell and Regenerative Medicine

Conferences:

11th Chinese Academy of Sciences–Max Planck Society Exploratory Round Table Conference on Organoids, Self-Organization, and Engineering, Shanghai
The 29th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2025), Adelaide, Australia
Tissue Engineering and Regenerative Medicine International Society – Asia-Pacific Conference (TERMIS-AP 2025), Wuhan
International Conference on Biofabrication 2025, Warsaw, Poland

Notable Events and Visits:

Topping-Out Ceremony for the Human Organ Physiopathology Emulation (HOPE) System and the Innovative Cell Technology R&D Platform
GU LAB at the 8th Science Festival of the Chinese Academy of Sciences
Visit and Academic Lecture by Prof. Uwe Marx, Founder and CSO of TissUse
Visit and IOZ Friday Seminar by Prof. Chwee Teck Lim, National University of Singapore
Visit and Life Science Forum Lecture by Associate Prof. Arnold Lining Ju, University of Sydney

Graduate Students:

Xiyuan Zhao, Tingting Fan, Yifan Hou, Yifan Wang, Carla Serra Colomer

2024

Awards:

Third Place at the 4th Tug of War, Beijing Institute for Stem Cell and Regenerative Medicine

Conferences:

18th International Conference on Biomedical Engineering (ICBME 2024), Singapore
International Conference on Biofabrication (Biofabrication 2024), Fukuoka, Japan
2024 International Symposium on Microphysiological Systems (MPS 2024), Sanya
The 12th World Biomaterials Congress (WBC 2024), Daegu, South Korea

Notable Visits:

Visit by a Delegation from the International Technology Department of the UK Foreign, Commonwealth & Development Office
Visit and HOPE Lecture by Prof. Donald E. Ingber, Founding Director of the Wyss Institute at Harvard University

Graduate Students:

Haitao Guo, Juan Wu

2023

Awards:

2023 Australia China Alumni Award for Research and Science (Judges’ Commendation and Winner), Australia China Alumni Association
2023 Excellent Final Evaluation, Hundred Talents Program of the Chinese Academy of Sciences（百人计划结题优秀）
2023 Outstanding Young Talents of “Phoenix Project” in Chaoyang District, Beijing

Conferences:

TERMIS-AP, 2023
International Conference on Biofabrication 2023, Saskatoon, Canada
The 6th National Conference on Developmental Biology, Hohhot
ASBTE 2023

Graduate Students:

Shuyu Zhang, Shenglong Ding, Minxuan Jia, Jingmin An

Before 2022

Awards:

2022: Distinguished Young Investigator awarded by the Chinese Society of Stem Cell Research (CSSCR)
2022: Excellent Young Scientists Fund awarded by the National Natural Science Foundation of China (NSFC).

Conferences:

The 10th Annual Meeting of CSSCR
ICBME 2019
TERMIS-AP & AMBC7 Congress 2019

Graduate Students:

Biao Song, Tingting Fan, Xia Li