People
Dr Gu is currently appointed as a Full Professor, Director of Chinese Academy of Sciences (CAS) Engineering Lab for Intelligent Organ Manufacturing and group leader of Bioinspired Engineering, at Institute for Stem Cell and Regeneration (ISCR) | Institute of Zoology (IOZ), CAS. Dr Gu has interdisciplinary training in materials chemistry and stem cells. His first doctoral career (2009-2013) is mainly engaged in research on stem cells at Northeast Agricultural University and Chinese Academy of Sciences. He completed a second PhD (2013-2017) in Chemistry at University of Wollongong (UOW) followed by being appointed as an Associate Professor at IOZ, CAS and establishing his lab, Bioinspired Engineering. He became Full Professor at IOZ, CAS at the end of 2019. Prof Gu focuses on developing novel biomaterials and advanced technologies, 3D/4D bioprinting to regulate stem cell fate, fabrication of functional 3D organs and even live organisms in vitro. These studies are applied to understand the mechanism of life and establish novel therapeutic methodologies. Prof Gu has previously published 33 first-author and corresponding author peer-reviewed journal articles, including Adv. Funct. Meter., Adv. Sci., Angew. Chem. Int. Ed., Materials Horizons, Adv. Healthc. Mater. etc., mostly on bioprinting, biofabrication, biomaterials and stem cell engineering over the past 5 years. Furthermore, Prof Gu has been invited to finish 3 book chapters and co-inventor on seven patents.
Selected Prizes, awards and honors
• 2022 Chinese Society of Stem Cell Research (CSSCR) Young Investigator Award
• 2022 Excellent Young Scientists Fund, National Natural Science Foundation of China (NSFC) （基金委优青）
• 2020 Final Evaluation of “Hundred Talents Program”, Chinese Academy of Sciences (CAS) （中科院百人择优）
• 2017 “Hundred Talents Program” Youth Talent of Chinese Academy of Sciences (CAS)
• 2017 UOW Outstanding Thesis
• 2017 Chinese Government Award for Outstanding Self-Financed Students Abroad
Principal Investigator
Ph.D. Professor
Dr Gu is currently appointed as a Full Professor, Director of Chinese Academy of Sciences (CAS) Engineering Lab for Intelligent Organ Manufacturing and group leader of Bioinspired Engineering, at Institute for Stem Cell and Regeneration (ISCR) | Institute of Zoology (IOZ), CAS. Dr Gu has interdisciplinary training in materials chemistry and stem cells. His first doctoral career (2009-2013) is mainly engaged in research on stem cells at Northeast Agricultural University and Chinese Academy of Sciences. He completed a second PhD (2013-2017) in Chemistry at University of Wollongong (UOW) followed by being appointed as an Associate Professor at IOZ, CAS and establishing his lab, Bioinspired Engineering. He became Full Professor at IOZ, CAS at the end of 2019. Prof Gu focuses on developing novel biomaterials and advanced technologies, 3D/4D bioprinting to regulate stem cell fate, fabrication of functional 3D organs and even live organisms in vitro. These studies are applied to understand the mechanism of life and establish novel therapeutic methodologies. Prof Gu has previously published 33 first-author and corresponding author peer-reviewed journal articles, including Adv. Funct. Meter., Adv. Sci., Angew. Chem. Int. Ed., Materials Horizons, Adv. Healthc. Mater. etc., mostly on bioprinting, biofabrication, biomaterials and stem cell engineering over the past 5 years. Furthermore, Prof Gu has been invited to finish 3 book chapters and co-inventor on seven patents.
Selected Prizes, awards and honors
• 2022 Chinese Society of Stem Cell Research (CSSCR) Young Investigator Award
• 2022 Excellent Young Scientists Fund, National Natural Science Foundation of China (NSFC) （基金委优青）
• 2020 Final Evaluation of “Hundred Talents Program”, Chinese Academy of Sciences (CAS) （中科院百人择优）
• 2017 “Hundred Talents Program” Youth Talent of Chinese Academy of Sciences (CAS)
• 2017 UOW Outstanding Thesis
• 2017 Chinese Government Award for Outstanding Self-Financed Students Abroad
Principal Investigator
Ph.D. Professor
OUR Team
Postdoctoral Associates
Postdoctoral Associate
XINHUAN got her B.S and M.S in chemistry at Yangzhou University. In 2019, she obtained her Doctor’s degree in physical chemistry at the University of Chinese Academy of Sciences. There, she designed material based composites and novel structures with visible-light response properties. After that, she joined Gu lab for postdoctoral training, Institute of Zoology, Chinese Academy of Sciences.
Research Interest:
Designing biopolymer-based micro-hydrogel for applications in constructing vascular networks.
Postdoctoral Associate
SHEN got his B.S degree in Pharmaceutical Engineering at Yunnan University. Then, he successfully obtained his M.S and Ph.D. degrees in Chemical Engineering at the New Jersey Institute of Technology in 2016 and 2020. During his doctoral studies, he focused on developing novel inks and approaches for printing tissues and organs. In 2020, He joined Dr. Gu’s lab as a postdoc.
Research Interest:
Bioprinting of large-scale vascularized tissue/organs
Shuyu Zhang
Postdoctoral Associate
SHUYU got her B.S degree in Pharmaceutical Analysis at Beijing University of Chinese Medicine. Then, she was recommended to the Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, and obtained a Ph.D. degree in pharmacology in 2018. During her doctoral period, she conducted retrospective or prospective clinical trials on anti-coagulant and anesthetic drugs to develop personalized dosing algorithms based on pharmacogenomic or metabolic findings. After graduation, she had experience in Individualized Medicine implementation in a 3A hospital and then drug development in a high-tech enterprise. In 2020, she joined Dr. Gu’s lab as a joint postdoc.
Research Interest:
Pharmacokinetic/Pharmacodynamic modeling based on Organs-on-chips.
Postdoctoral Associate
2022.08 till now, Institute of Zoology, Chinese Academy of Sciences, Postdoctoral Associate
2017.09 – 2022.07 Savaid Medical School, University of Chinese Academy of Sciences, major in regenerative medicine, Ph.D.
2016.03 – 2017.08 Institute of Zoology, Chinese Academy of Sciences, joint undergraduate.
2013.09 – 2016.02, Hebei University, major in biological science, B.S.
Research Interest:
Integrated system to study vascular networks and to print multi-materials.
Heng Liu
Postdoctoral Associate
HENG completed his B.S. in Clinical Medicine at Jining Medical College in 2016, followed by postgraduate studies in Orthopaedics at Bethune Medical College of Jilin University, where he received his Master’s degree in 2019. He then pursued his doctorate at the University of Munich, sponsored by the China Scholarship Council (CSC), and earned his Dr. Med. degree in 2022. Upon returning to China, he became a joint postdoctoral fellow at Beijing Jishuitan Hospital and the Institute of Zoology, Chinese Academy of Sciences, by joining the Gu lab in 2023.
Research Interest:
Bone and cartilage tissue engineering；
Treatment of bone infections；
Osteoporosis therapy；
Development of bone cement materials.
Visiting Students / Scholars
Rui Gao
Graduate Student
RUI completed his master’s in Instrument Science and Technology at the North University of China in 2023. He is currently visiting and studying in Gu Lab.
Research Interest:
Research on the Mechanism of Thrombosis
Brain-computer interface（BCI）
Renyuan Sun
Graduate Student
2023.07 till now, Institute of Zoology, Chinese Academy of Sciences.
2020.09 – 2023.06, Hebei University of Technology, major in biomedical engineering, M.S.
2016.09 – 2020.06, Hebei University of Technology, major in electrical engineering and automation, B.S
Research Interest:
Biomedical materials, EHD (electrohydrodynamic) printing and electrospinning.
Ph.D. STUDENTS
Joint Doctoral Candidate
2020.09 till now, Institute of Zoology, Chinese Academy of Sciences, Beijing TongRen Hospital of Capital Medical University, major in Orthopedic Surgery.
2017.09 – 2020.06, Zhongshan Hospital, Fudan university, major in Orthopedic Surgery, M.M.
2012.09 – 2017.06, Nanchang University, major in clinical medicine, B.S.
Research Interest:
Bionic hydrogel for applications in cartilage regeneration by using 3D printing.
Zili Gao
Doctoral Candidate
2018.09 till now, Savaid Medical School, University of Chinese Academy of Sciences, major in regenerative medicine.
2014.09 – 2018.07, Shandong Agricultural University, major in biotechnology, B.S.
Research Interest:
Microspheres & Biointerfaces & Functional Units
Tingting Fan
Doctoral Candidate
2021.09 till now, Institute of Zoology, Chinese Academy of Sciences.
2018.09 – 2021.07, Institute of Zoology, Chinese Academy of Sciences, major in regenerative medicine, M.D.
2014.09 – 2018.07, Hebei University, major in Biological sciences, B.S.
Research Interest:
Skeletal muscle regeneration using 3D bioprinting technology.
Doctoral Candidate
2019.09 till now, Institute of Zoology, Chinese Academy of Sciences.
2018.03 – 2019.06 Institute of Zoology, Chinese Academy of Sciences, joint undergraduate.
2015.09 – 2018.01 Hebei University, major in biological science.
Research Interest:
Hard-soft composition bioink
Doctoral Candidate
KAI acquired his master’s degree in 2019 majored in Materials Engineering at the Viterbi School of Engineering at the University of Southern California (USC). From 2013 to 2017, he studied at the University of Science and Technology Beijing and majored in Materials Science and Engineering.
Research Interest:
Complicated printing paths for bio-gradience and bio-anisotropy to be used in heart construction.
Tan Jia
Joint Doctoral Candidate
2021.09 till now, Institute of Zoology, Chinese Academy of Sciences
2017.9 – 2021.7, Shandong University
Research Interest:
Manipulate cell morphological characteristics in 3D printing
Xiyuan Zhao
Doctoral Candidate
2020.06 till now, Institute of Zoology, Chinese Academy of Sciences, mainly engages in the preparation of microcarriers.
2017.09 – 2020.06, studied at Beijing University of Chemical Technology with a master’s degree in materials science and engineering. The main work is to characterize and study the microparticles, existing forms and chemical composition of rubber, and change the properties of materials by changing the structure.
Research Interest:
Microgel system development for stem cell culture and printing
Jialin Hu
Doctoral Candidate
2022.09 till now, Institute of Zoology, Chinese Academy of Sciences.
2019.09 – 2022.06 Henan University, joint national laboratory for antibody drug engineering
2015.09 – 2019.06 Zhejiang Normal University, College of Chemistry and Life Science
Research Interest:
Multidirectional differentiation of embryonic stem cells in the 3D environment
DIMING ZHAO
Joint Doctoral Candidate
2022.09 till now, Institute of Zoology, Chinese Academy of Sciences; Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases, major in Cardiovascular Surgery.
2014.09 – 2022.06, Shandong University, major in cardiovascular surgery, B.S. & M.D.
Research Interest:
Tissue-engineered heart valve using 3D bioprinting technology.
Mingjian Chen
Joint Doctoral Candidate
2022.09 till now, Institute of Zoology, Chinese Academy of Sciences; Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases, major in Cardiovascular Surgery.
2019.09 – 2022.06, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases, major in Cardiovascular Surgery, M.D.
2014.09 – 2019.06, Guangzhou Medical University, major in clinical medicine, B.S.
Research Interest:
Tissue-engineered heart valve using 3D bioprinting technology.
Juan Zhang
Joint Doctoral Candidate
2023.06 till now, Institute of Zoology, Chinese Academy of Sciences; Northeast Agriculture University
2020.10 – 2023.06, Hubei University; Institute of Biophysics, Chinese Academy of Sciences
Research Interest:
Using stem cells to construct a brain development model in vitro
Master's Students
Minxuan Jia
Graduate Student
2020.06 till now, Institute of Zoology, Chinese Academy of Sciences, major in regenerative medicine.
Research Interest:
Materials development to study cell migration perpendicular to the interface
Jinqiu Zhangjing
Joint Graduate Student
2020.09 till now, Northeast Agriculture University, Harbin.
2018.05 – 2019.08, Research Assistant, Gulab, IOZ, CAS.
Research Interest:
Stem cells & Developmental biology & Biofabrication
Haitao Guo
Graduate Student
2021.09 till now, Institute of Zoology, Chinese Academy of Sciences.
2017.9 – 2021.6, Nanchang University, major in Material Forming and Control Engineering.
Research Interest:
Biomedical Materials and 3D printing preparation.
Juan Wu
Graduate Student
2021.09 till now, Institute of Zoology, Chinese Academy of Sciences.
2017.09 – 2021.06, Tianjin Medical University, major in Biomedical Engineering.
Research Interest:
Biomedical Materials and 3D printing preparation.
Jingmin An
Joint Graduate Student
2021.09 till now, Northeast Agricultural University.
Research Interest:
Artificial-Intelligence-Assisted Biofabrication
Yifan Wang
Graduate Student
2022.02 till now, doing the undergraduate graduation project. 2018.09 till now, Undergraduate in Nanjing Normal University, majoring in biological science.
Research Interest:
Construction of bionic small-diameter blood vessel based on biomaterials
Guoshi Xu
Graduate Student
2022.07 till now, Institute of Zoology, Chinese Academy of Sciences.
2018.08 – 2022.06, Southeast University, major in Biomedical Engineering.
Research Interest:
Biomedical Materials and Microfluidics
Yifan Hou
Graduate Student
2022.09 till now, Institute of Zoology, Chinese Academy of Sciences.
2017.9 – 2021.6, Southeast University, major in Biomedical Engineering.
Research Interest:
Biofabrication of vascularized tissue/organs
Rui Yuan
Joint Graduate Student
2020.09 till now, Jiangsu University, Zhenjiang. 2016.09-2020.06, Henan Polytechnic University, Jiaozuo.
Research Interest:
Electrocatalytic Oxygen Reduction Performance of Cobalt Porphyrin-based Complex
Dadi Sun
Joint Graduate Student
2022.09 till now, Institute of Zoology, Chinese Academy of Sciences, Beijing Tongren Hospital of Capital Medical University, major in Orthopedic Surgery.
2016.09 – 2021.06, Guangxi Medical University, major in clinical medicine, B.S.
Research Interest:
Haolin Chen
Graduate Student
2023.06 till now, Institute of Zoology, Chinese Academy of Science.
2018.09 – 2022.06, Shandong University, major in Material Science and Engineering.
Research Interest:
Machine-Learning-Assisted Biofabrication and Microfluidics
Shuxian Chen
Graduate Student
2023.06 till now, Institute of Zoology, Chinese Academy of Sciences.
2019.09 – 2023.06, Yangzhou University, major in Material Forming and Control Engineering.
Research Interest:
Construction of vascularized tissue by 3D bioprinting
Undergraduate Students
Yanyan Liu
Undergraduate Intern
2019.09 till now, Beijing Institute of Fashion Technology, major in Polymer Materials and Engineering
Research Interest:
3D printing preparation, Construction of vascularized tissue
Qixun Sun
Undergraduate Intern
2023.09 till now, Institute of Zoology, Chinese Academy of Sciences
2020.09 – 2023.09 Northeast Agriculture University major in biological science
Research Interests:
Artificial human tissue/organ production based on 3D printing
Uterus-free embryo growth
Staff
Lixun Zhou
Laboratory Manager
2019 till now, Institute of Zoology, Chinese Academy of Sciences, supervised and maintained the experiment order, managed experiment finance-related works, and secretary work of the lab.
2015.07 – 2019.06, lab manager, Institute of Genetics and Development Biology Chinese Academy of Sciences.
2016.09 – 2019.06, Joint-Postgraduates, Fujian Agriculture and Forestry University and Institute of Genetics and Development Biology Chinese Academy of Sciences, major in crop genetics and breeding.
Xiaolong Kou
Laboratory Engineer
XIAOLONG got his B.S and Ph.D. degrees at Jilin University in 2011 and 2016. During the doctoral period, he focused on AFM-based single molecular force spectroscopy and investigated telomere DNA structure. After graduation, he went to the Institute of Chemistry, the Chinese Academy of Sciences, worked as a postdoctoral associate. During his postdoc, he focused on the AFM-optical imaging system. He developed AFM based tip-enhanced CARS system and other super-resolution optical imaging systems. In 2022, he joined Gu’s group as an engineer.
Research Interest:
AFM-based imaging and force measurement. Optical imaging and optical engineering. Other biology and biochemistry-related researches.
Wenli Liu
Mechanical Engineer
2018.07 till now, Institute of Zoology, Chinese Academy of Sciences, 3D modeling, operation, and maintenance of 3D printers and related equipment.
Ruoyu Liu
Mechanical Engineer
2022.02 till now, Institute of Zoology, Chinese Academy of Sciences. 2017.09 – 2021.06, Xinjiang University, major in Mechanical Engineering.
Research Interest:
Experimental equipment design and fabrication